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肿瘤模型In vitro investigations into the roles of drug transporters and metabolizing enzymes in the disposition and drug interactions of dolutegravir, a HIV integrase inhibitor.

期刊:Drug metabolism and disposition: the biological fate of chemicals发表年份:2013作者:Melinda J Reese; Paul M Savina; Grant T Generaux; Helen Tracey; Joan E Humphreys; Eri Kanaoka; Lindsey O Webster; Kelly A Harmon; James D Clarke; Joseph W Polli

肿瘤模型Discovery and characterization of alamandine: a novel component of the renin-angiotensin system.

期刊:Circulation research发表年份:2013作者:Roberto Queiroga Lautner; Daniel C Villela; Rodrigo A Fraga-Silva; Neiva Silva; Thiago Verano-Braga; Fabiana Costa-Fraga; Joachim Jankowski; Vera Jankowski; Frederico Sousa; Andreia Alzamora; Everton Soares; Claudiane Barbosa; Frank Kjeldsen; Aline O

肿瘤模型Stat6 cooperates with Sp1 in controlling breast cancer cell proliferation by modulating the expression of p21(Cip1/WAF1) and p27 (Kip1).

期刊:Cellular oncology (Dordrecht, Netherlands)发表年份:2013作者:Min Wei; Bingya Liu; Qinlong Gu; Liping Su; Yingyan Yu; Zhenggang Zhu

肿瘤模型Antitumor activity of a duocarmycin analogue rationalized to be metabolically activated by cytochrome P450 1A1 in human transitional cell carcinoma of the bladder.

期刊:Molecular cancer therapeutics发表年份:2013作者:Mark Sutherland; Jason H Gill; Paul M Loadman; Jonathan P Laye; Helen M Sheldrake; Nicola A Illingworth; Mohammed N Alandas; Patricia A Cooper; Mark Searcey; Klaus Pors; Steve D Shnyder; Laurence H Patterson