药效评价Discovery and biological characterization of (2R,4S)-1'-acetyl-N-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl}-2-(4-fluoro-2-methylphenyl)-N-methyl-4,4'-bipiperidine-1-carboxamide as a new potent and selective neurokinin 1 (NK1) receptor antagonist
期刊：Journal of medicinal chemistry发表年份：2011作者：Romano Di Fabio; Giuseppe Alvaro; Cristiana Griffante; Domenica A Pizzi; Daniele Donati; Mario Mattioli; Zadeo Cimarosti; Giuseppe Guercio; Carla Marchioro; Stefano Provera; Laura Zonzini; Dino Montanari; Sergio Melotto; Philip A Gerrard; David G Tri