药效评价The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 (6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one) enhances synaptic plasticity and cognitive functi
期刊：Neuropharmacology发表年份：2011作者：P H Hutson; E N Finger; B C Magliaro; S M Smith; A Converso; P E Sanderson; D Mullins; L A Hyde; B K Eschle; Z Turnbull; H Sloan; M Guzzi; X Zhang; A Wang; D Rindgen; R Mazzola; J A Vivian; D Eddins; J M Uslaner; R Bednar; C Gambone; W Le-Mair; M J M