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代谢疾病Absorption, Metabolism, and Excretion, In Vitro Pharmacology, and Clinical Pharmacokinetics of Ozanimod, a Novel Sphingosine 1-Phosphate Receptor Modulator.

期刊:Drug metabolism and disposition: the biological fate of chemicals发表年份:2021作者:Sekhar Surapaneni; Usha Yerramilli; April Bai; Deepak Dalvie; Jennifer Brooks; Xiaomin Wang; Julie V Selkirk; Yingzhuo Grace Yan; Peijin Zhang; Richard Hargreaves; Gondi Kumar; Maria Palmisano; Jonathan Q Tran

代谢疾病Discovery of a Positive Allosteric Modulator of Cholecystokinin Action at CCK1R in Normal and Elevated Cholesterol.

期刊:Frontiers in endocrinology发表年份:2021作者:Kaleeckal G Harikumar; Thomas Coudrat; Aditya J Desai; Maoqing Dong; Daniela G Dengler; Sebastian G B Furness; Arthur Christopoulos; Denise Wootten; Eduard A Sergienko; Patrick M Sexton; Laurence J Miller

代谢疾病Initial hazard assessment of ethyl(dimethyl)(tetradecyl)ammonium ethyl sulfate: Genotoxicity tests and combined repeated-dose and reproductive/developmental toxicity screening in rats.

期刊:Regulatory toxicology and pharmacology : RTP发表年份:2021作者:Mariko Matsumoto; Masao Takano; Michihito Takabe; Noriko Yamaguchi; Takako Iso; Yoshiyuki Shigeta; Yasumasa Murata; Nozomu Hirose; Kaoru Inoue; Akihiko Hirose

代谢疾病The effect of fatty diacid acylation of human PYY3-36 on Y2 receptor potency and half-life in minipigs.

期刊:Scientific reports发表年份:2021作者:Søren Østergaard; Johan F Paulsson; Jacob Kofoed; Franziska Zosel; Jørgen Olsen; Claus Bekker Jeppesen; Jane Spetzler; Lars Ynddal; Luise Gram Schleiss; Berit Østergaard Christoffersen; Kirsten Raun; Ulrich Sensfuss; Flemming Seier Nielsen; Rasmus Jø