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代谢疾病Pharmacodynamic and pharmacokinetic profiles of a neurotensin receptor type 2 (NTS2) analgesic macrocyclic analog.

期刊:Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie发表年份:2021作者:Magali Chartier; Michael Desgagné; Marc Sousbie; Charles Rumsby; Lucie Chevillard; Léa Théroux; Lounès Haroune; Jérôme Côté; Jean-Michel Longpré; Pierre-Luc Boudreault; Éric Marsault; Philippe Sarret

代谢疾病Development of an orally delivered GLP-1 receptor agonist through peptide engineering and drug delivery to treat chronic disease.

期刊:Scientific reports发表年份:2021作者:Sergei Pechenov; Jefferson Revell; Sarah Will; Jacqueline Naylor; Puneet Tyagi; Chandresh Patel; Lihuan Liang; Leo Tseng; Yue Huang; Anton I Rosenbaum; Kemal Balic; Anish Konkar; Joseph Grimsby; J Anand Subramony

代谢疾病Discovery of a novel series of indolinylpyrimidine-based GPR119 agonists: Elimination of ether-a-go-go-related gene liability using a hydrogen bond acceptor-focused approach.

期刊:Bioorganic & medicinal chemistry发表年份:2021作者:Masahiro Kamaura; Osamu Kubo; Hiromichi Sugimoto; Naoyoshi Noguchi; Hirohisa Miyashita; Shinichi Abe; Kae Matsuda; Yoshiyuki Tsujihata; Tomoyuki Odani; Shinji Iwasaki; Toshiki Murata; Kenjiro Sato

代谢疾病Development of 18F-Labeled Radiotracers for PET Imaging of the Adenosine A2A Receptor: Synthesis, Radiolabeling and Preliminary Biological Evaluation.

期刊:International journal of molecular sciences发表年份:2021作者:Thu Hang Lai; Susann Schröder; Magali Toussaint; Sladjana Dukić-Stefanović; Mathias Kranz; Friedrich-Alexander Ludwig; Steffen Fischer; Jörg Steinbach; Winnie Deuther-Conrad; Peter Brust; Rareş-Petru Moldovan