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药效评价Inorganic mercury causes pancreatic beta-cell death via the oxidative stress-induced apoptotic and necrotic pathways.

期刊：Toxicology and applied pharmacology发表年份：2010作者：Ya Wen Chen; Chun Fa Huang; Ching Yao Yang; Cheng Chieh Yen; Keh Sung Tsai; Shing Hwa Liu
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药效评价Importance of neonatal FcR in regulating the serum half-life of therapeutic proteins containing the Fc domain of human IgG1: a comparative study of the affinity of monoclonal antibodies and Fc-fusion proteins to human neonatal FcR.

期刊：Journal of immunology (Baltimore, Md. : 1950)发表年份：2010作者：Takuo Suzuki; Akiko Ishii-Watabe; Minoru Tada; Tetsu Kobayashi; Toshie Kanayasu-Toyoda; Toru Kawanishi; Teruhide Yamaguchi
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药效评价TrkB and TrkC agonist antibodies improve function, electrophysiologic and pathologic features in Trembler J mice.

期刊：Experimental neurology发表年份：2010作者：Zarife Sahenk; Gloria Galloway; Chris Edwards; Vinod Malik; Brian K Kaspar; Amy Eagle; Brent Yetter; Alison Forgie; David Tsao; John C Lin
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药效评价Discovery of the dual orexin receptor antagonist [(7R)-4-(5-chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone (MK-4305) for the treatment of insomnia.

期刊：Journal of medicinal chemistry发表年份：2010作者：Christopher D Cox; Michael J Breslin; David B Whitman; John D Schreier; Georgia B McGaughey; Michael J Bogusky; Anthony J Roecker; Swati P Mercer; Rodney A Bednar; Wei Lemaire; Joseph G Bruno; Duane R Reiss; C Meacham Harrell; Kathy L Murphy; Susan L
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