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药效评价Synthesis and biological evaluation of bivalent ligands for the cannabinoid 1 receptor.

期刊:Journal of medicinal chemistry发表年份:2010作者:Yanan Zhang; Anne Gilliam; Rangan Maitra; M Imad Damaj; Julianne M Tajuba; Herbert H Seltzman; Brian F Thomas

药效评价A common intracellular allosteric binding site for antagonists of the CXCR2 receptor.

期刊:British journal of pharmacology发表年份:2010作者:K Salchow; M E Bond; S C Evans; N J Press; S J Charlton; P A Hunt; M E Bradley

药效评价Discovery of novel allosteric modulators of metabotropic glutamate receptor subtype 5 reveals chemical and functional diversity and in vivo activity in rat behavioral models of anxiolytic and antipsychotic activity.

期刊:Molecular pharmacology发表年份:2010作者:Alice L Rodriguez; Mark D Grier; Carrie K Jones; Elizabeth J Herman; Alexander S Kane; Randy L Smith; Richard Williams; Ya Zhou; Joy E Marlo; Emily L Days; Tasha N Blatt; Satyawan Jadhav; Usha N Menon; Paige N Vinson; Jerri M Rook; Shaun R Stauffer;

药效评价Target promiscuity and heterogeneous effects of tarantula venom peptides affecting Na+ and K+ ion channels.

期刊:The Journal of biological chemistry发表年份:2010作者:Elisa Redaelli; Rita Restano Cassulini; Deyanira Fuentes Silva; Herlinda Clement; Emanuele Schiavon; Fernando Z Zamudio; George Odell; Annarosa Arcangeli; Jeffrey J Clare; Alejandro Alagón; Ricardo C Rodríguez de la Vega; Lourival D Possani; Enzo Wan