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药效评价Evaluation of cannabinoid receptor 2 and metabotropic glutamate receptor 1 functional responses using a cell impedance-based technology.

期刊：Journal of biomolecular screening发表年份：2010作者：Paola Scandroglio; Rossella Brusa; Gianluca Lozza; Isabella Mancini; Roberta Petrò; Angelo Reggiani; Massimiliano Beltramo
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药效评价Discovery of a novel 5-HT(3) antagonist/5-HT(1A) agonist 3-amino-5,6,7,8-tetrahydro-2-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}quinazolin-4(3H)-one (TZB-30878) as an orally bioavailable agent for irritable bowel syndrome.

期刊：Journal of medicinal chemistry发表年份：2010作者：Akira Asagarasu; Teruaki Matsui; Hiroyuki Hayashi; Satoru Tamaoki; Yukinao Yamauchi; Kouichi Minato; Michitaka Sato
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药效评价In vitro and in vivo characterization of JNJ-31020028 (N-(4-{4-[2-(diethylamino)-2-oxo-1-phenylethyl]piperazin-1-yl}-3-fluorophenyl)-2-pyridin-3-ylbenzamide), a selective brain penetrant small molecule antagonist of the neuropeptide Y Y(2) receptor.

期刊：Psychopharmacology发表年份：2010作者：James R Shoblock; Natalie Welty; Diane Nepomuceno; Brian Lord; Leah Aluisio; Ian Fraser; S Timothy Motley; Steve W Sutton; Kirsten Morton; Ruggero Galici; John R Atack; Lisa Dvorak; Devin M Swanson; Nicholas I Carruthers; Curt Dvorak; Timothy W Loven
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药效评价Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists.

期刊：The Journal of pharmacology and experimental therapeutics发表年份：2010作者：Kasper B Hansen; Praseeda Mullasseril; Sara Dawit; Natalie L Kurtkaya; Hongjie Yuan; Katie M Vance; Anna G Orr; Trine Kvist; Kevin K Ogden; Phuong Le; Kimberly M Vellano; Iestyn Lewis; Serdar Kurtkaya; Yuhong Du; Min Qui; T J Murphy; James P Snyder;
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