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肿瘤模型SG2285, a novel C2-aryl-substituted pyrrolobenzodiazepine dimer prodrug that cross-links DNA and exerts highly potent antitumor activity.

期刊：Cancer research发表年份：2010作者：John A Hartley; Anzu Hamaguchi; Marissa Coffils; Christopher R H Martin; Marie Suggitt; Zhizhi Chen; Stephen J Gregson; Luke A Masterson; Arnaud C Tiberghien; Janet M Hartley; Christopher Pepper; Thet Thet Lin; Christopher Fegan; David E Thurston; Ph
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肿瘤模型Replacement of imidazolyl by pyridyl in biphenylmethylenes results in selective CYP17 and dual CYP17/CYP11B1 inhibitors for the treatment of prostate cancer.

期刊：Journal of medicinal chemistry发表年份：2010作者：Qingzhong Hu; Carsten Jagusch; Ulrike E Hille; Jörg Haupenthal; Rolf W Hartmann
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肿瘤模型Implication of the ERK pathway on the post-transcriptional regulation of VEGF mRNA stability.

期刊：Methods in molecular biology (Clifton, N.J.)发表年份：2010作者：Khadija Essafi-Benkhadir; Jacques Pouysségur; Gilles Pagès
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肿瘤模型Targeting the polyamine transport system with benzazepine- and azepine-polyamine conjugates.

期刊：Journal of medicinal chemistry发表年份：2010作者：Sophie Tomasi; Jacques Renault; Bénédicte Martin; Stephane Duhieu; Virginie Cerec; Myriam Le Roch; Philippe Uriac; Jean-Guy Delcros
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