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病毒感染Monovalent SARS-COV-2 mRNA vaccine using optimal UTRs and LNPs is highly immunogenic and broadly protective against Omicron variants.

期刊:Proceedings of the National Academy of Sciences of the United States of America发表年份:2023作者:Zhongfeng Ye; Srinivasa Reddy Bonam; Lindsay G A McKay; Jessica A Plante; Jordyn Walker; Yu Zhao; Changfeng Huang; Jinjin Chen; Chutian Xu; Yamin Li; Lihan Liu; Joseph Harmon; Shuliang Gao; Donghui Song; Zhibo Zhang; Kenneth S Plante; Anthony Griffit

病毒感染An intranasal vaccine comprising SARS-CoV-2 spike receptor-binding domain protein entrapped in mannose-conjugated chitosan nanoparticle provides protection in hamsters.

期刊:Scientific reports发表年份:2023作者:Kairat Tabynov; Maxim Solomadin; Nurkeldi Turebekov; Meruert Babayeva; Gleb Fomin; Ganesh Yadagiri; Sankar Renu; Toktassyn Yerubayev; Nikolai Petrovsky; Gourapura J Renukaradhya; Kaissar Tabynov

病毒感染Previous infection with seasonal coronaviruses does not protect male Syrian hamsters from challenge with SARS-CoV-2.

期刊:Nature communications发表年份:2023作者:Magen E Francis; Ethan B Jansen; Anthony Yourkowski; Alaa Selim; Cynthia L Swan; Brian K MacPhee; Brittany Thivierge; Rachelle Buchanan; Kerry J Lavender; Joseph Darbellay; Matthew B Rogers; Jocelyne Lew; Volker Gerdts; Darryl Falzarano; Danuta M Sko

病毒感染An intranasal nanoparticle STING agonist protects against respiratory viruses in animal models.

期刊:Nature communications发表年份:2024作者:Ankita Leekha; Arash Saeedi; Monish Kumar; K M Samiur Rahman Sefat; Melisa Martinez-Paniagua; Hui Meng; Mohsen Fathi; Rohan Kulkarni; Kate Reichel; Sujit Biswas; Daphne Tsitoura; Xinli Liu; Laurence J N Cooper; Courtney M Sands; Vallabh E Das; Manu S