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药效评价The KCNQ2/3 selective channel opener ICA-27243 binds to a novel voltage-sensor domain site.

期刊:Neuroscience letters发表年份:2009作者:Karen Padilla; Alan D Wickenden; Aaron C Gerlach; Ken McCormack

药效评价Functionalized congeners of A3 adenosine receptor-selective nucleosides containing a bicyclo[3.1.0]hexane ring system.

期刊:Journal of medicinal chemistry发表年份:2009作者:Dilip K Tosh; Moshe Chinn; Andrei A Ivanov; Athena M Klutz; Zhan-Guo Gao; Kenneth A Jacobson

药效评价Molecular pharmacology of the amiloride analog 3-amino-6-chloro-5-[(4-chloro-benzyl)amino]-n-[[(2,4-dimethylbenzyl)-amino]iminomethyl]-pyrazinecarboxamide (CB-DMB) as a pan inhibitor of the Na+-Ca2+ exchanger isoforms NCX1, NCX2, and NCX3 in stably t

期刊:The Journal of pharmacology and experimental therapeutics发表年份:2009作者:Agnese Secondo; Anna Pannaccione; Pasquale Molinaro; Paolo Ambrosino; Pellegrino Lippiello; Alba Esposito; Maria Cantile; Priti R Khatri; Daniela Melisi; Gianfranco Di Renzo; Lucio Annunziato

药效评价JNK and ceramide kinase govern the biogenesis of lipid droplets through activation of group IVA phospholipase A2.

期刊:The Journal of biological chemistry发表年份:2009作者:Albert Gubern; Miquel Barceló-Torns; David Barneda; José M López; Roser Masgrau; Fernando Picatoste; Charles E Chalfant; Jesús Balsinde; María A Balboa; Enrique Claro