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代谢疾病Discovery of a Potent, Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitor (HSK0935) for the Treatment of Type 2 Diabetes.

期刊：Journal of medicinal chemistry发表年份：2017作者：Yao Li; Zongjun Shi; Lei Chen; Suxin Zheng; Sheng Li; Bo Xu; Zhenhong Liu; Jianyu Liu; Chongyang Deng; Fei Ye
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代谢疾病Structural development of 1,2,3,4-tetrahydroisoquinoline-type positive allosteric modulators of prostacyclin receptor (IPPAMs) to improve metabolic stability, and investigation of metabolic fate.

期刊：Bioorganic & medicinal chemistry letters发表年份：2017作者：Hiroyuki Miyachi; Toshifumi Suzuki; Riyo Imamura; Tetsuo Nagano; Takayoshi Okabe
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代谢疾病Discovery of novel 5-oxa-2,6-diazaspiro[3.4]oct-6-ene derivatives as potent, selective, and orally available somatostatin receptor subtype 5 (SSTR5) antagonists for treatment of type 2 diabetes mellitus.

期刊：Bioorganic & medicinal chemistry发表年份：2017作者：Hideki Hirose; Takeshi Yamasaki; Masaki Ogino; Ryo Mizojiri; Yumiko Tamura-Okano; Hiroaki Yashiro; Yo Muraki; Yoshihide Nakano; Jun Sugama; Akito Hata; Shinji Iwasaki; Masanori Watanabe; Tsuyoshi Maekawa; Shizuo Kasai
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代谢疾病N-glycolyl groups of nonhuman chondroitin sulfates survive in ancient fossils.

期刊：Proceedings of the National Academy of Sciences of the United States of America发表年份：2017作者：Anne K Bergfeld; Roger Lawrence; Sandra L Diaz; Oliver M T Pearce; Darius Ghaderi; Pascal Gagneux; Meave G Leakey; Ajit Varki
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