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药效评价Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity.

期刊:The Journal of pharmacology and experimental therapeutics发表年份:2005作者:Richard H P Porter; Georg Jaeschke; Will Spooren; Theresa M Ballard; Bernd Büttelmann; Sabine Kolczewski; Jens-Uwe Peters; Eric Prinssen; Jürgen Wichmann; Eric Vieira; Andreas Mühlemann; Silvia Gatti; Vincent Mutel; Pari Malherbe

药效评价Signal transduction during environmental stress: InsP8 operates within highly restricted contexts.

期刊:Cellular signalling发表年份:2005作者:Kuicheon Choi; Elahe Mollapour; Stephen B Shears

药效评价Metabotropic glutamate receptor 8-expressing nerve terminals target subsets of GABAergic neurons in the hippocampus.

期刊:The Journal of neuroscience : the official journal of the Society for Neuroscience发表年份:2005作者:Francesco Ferraguti; Thomas Klausberger; Philip Cobden; Agnes Baude; J David B Roberts; Peter Szucs; Ayae Kinoshita; Ryuichi Shigemoto; Peter Somogyi; Yannis Dalezios

药效评价A selective metabotropic glutamate receptor 7 agonist: activation of receptor signaling via an allosteric site modulates stress parameters in vivo.

期刊:Proceedings of the National Academy of Sciences of the United States of America发表年份:2005作者:Kayo Mitsukawa; Rina Yamamoto; Silvio Ofner; Joachim Nozulak; Oliver Pescott; Snezana Lukic; Natacha Stoehr; Cedric Mombereau; Rainer Kuhn; Kevin H McAllister; Herman van der Putten; John F Cryan; Peter J Flor