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代谢疾病Elimination of a cholecystokinin receptor agonist 'trigger' in an effort to develop positive allosteric modulators without intrinsic agonist activity.

期刊:Bioorganic & medicinal chemistry letters发表年份:2015作者:Aditya J Desai; Brad R Henke; Laurence J Miller

代谢疾病Combined Optical Coherence and Fluorescence Microscopy to assess dynamics and specificity of pancreatic beta-cell tracers.

期刊:Scientific reports发表年份:2015作者:Corinne Berclaz; Christophe Pache; Arno Bouwens; Daniel Szlag; Antonio Lopez; Lieke Joosten; Selen Ekim; Maarten Brom; Martin Gotthardt; Anne Grapin-Botton; Theo Lasser

代谢疾病Molecular Mechanism of Action of Triazolobenzodiazepinone Agonists of the Type 1 Cholecystokinin Receptor. Possible Cooperativity across the Receptor Homodimeric Complex.

期刊:Journal of medicinal chemistry发表年份:2015作者:Aditya J Desai; Polo C H Lam; Andrew Orry; Ruben Abagyan; Arthur Christopoulos; Patrick M Sexton; Laurence J Miller

代谢疾病Synthesis and biological evaluations of novel endomorphin analogues containing α-hydroxy-β-phenylalanine (AHPBA) displaying mixed μ/δ opioid receptor agonist and δ opioid receptor antagonist activities.

期刊:European journal of medicinal chemistry发表年份:2015作者:Miao Hu; Marc A Giulianotti; Jay P McLaughlin; Jiaan Shao; Ginamarie Debevec; Laura E Maida; Phaedra Geer; Margaret Cazares; Jaime Misler; Ling Li; Colette Dooley; Michelle L Ganno; Shainnel O Eans; Elisa Mizrachi; Radleigh G Santos; Austin B Yongye;