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代谢疾病Combining MK626, a novel DPP-4 inhibitor, and low-dose monoclonal CD3 antibody for stable remission of new-onset diabetes in mice.

期刊:PloS one发表年份:2014作者:Lei Ding; Conny A Gysemans; Geert Stangé; Yves Heremans; Yixing Yuchi; Tatiana Takiishi; Hannelie Korf; Marie Chintinne; Richard D Carr; Harry Heimberg; Daniel Pipeleers; Chantal Mathieu

代谢疾病A novel pancreatic β-cell targeting bispecific-antibody (BsAb) can prevent the development of type 1 diabetes in NOD mice.

期刊:Clinical immunology (Orlando, Fla.)发表年份:2014作者:Palash Bhattacharya; Jilao Fan; Christine Haddad; Abdul Essani; Anupama Gopisetty; Hatem A Elshabrawy; Chenthamarakshan Vasu; Bellur S Prabhakar

代谢疾病Increasing fatty acid oxidation remodels the hypothalamic neurometabolome to mitigate stress and inflammation.

期刊:PloS one发表年份:2014作者:Joseph W McFadden; Susan Aja; Qun Li; Veera V R Bandaru; Eun-Kyoung Kim; Norman J Haughey; Francis P Kuhajda; Gabriele V Ronnett

代谢疾病G protein-coupled bile acid receptor 1 stimulation mediates arterial vasodilation through a K(Ca)1.1 (BK(Ca))-dependent mechanism.

期刊:The Journal of pharmacology and experimental therapeutics发表年份:2014作者:Ryan M Fryer; Khing Jow Ng; Suzanne G Nodop Mazurek; Lori Patnaude; Donna J Skow; Akalushi Muthukumarana; Kyle E Gilpin; Roger M Dinallo; Daniel Kuzmich; John Lord; Sulagna Sanyal; Hui Yu; Christian Harcken; Matthew A Cerny; Eugene R Hickey; Louise K