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药效评价Discovery of CC chemokine receptor-3 (CCR3) antagonists with picomolar potency.

期刊:Journal of medicinal chemistry发表年份:2005作者:George V De Lucca; Ui Tae Kim; Brian J Vargo; John V Duncia; Joseph B Santella; Daniel S Gardner; Changsheng Zheng; Ann Liauw; Zhang Wang; George Emmett; Dean A Wacker; Patricia K Welch; Maryanne Covington; Nicole C Stowell; Eric A Wadman; Anuk M Das

药效评价Dipeptides as effective prodrugs of the unnatural amino acid (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740), a selective group II metabotropic glutamate receptor agonist.

期刊:Journal of medicinal chemistry发表年份:2005作者:Ana Belén Bueno; Iván Collado; Alfonso de Dios; Carmen Domínguez; José Alfredo Martín; Luisa M Martín; María Angeles Martínez-Grau; Carlos Montero; Concepción Pedregal; John Catlow; D Scott Coffey; Michael P Clay; Anne H Dantzig; Terry Lindstrom; Jam

药效评价Valerian extract and valerenic acid are partial agonists of the 5-HT5a receptor in vitro.

期刊:Brain research. Molecular brain research发表年份:2005作者:Birgit M Dietz; Gail B Mahady; Guido F Pauli; Norman R Farnsworth

药效评价Sumanirole, a highly dopamine D2-selective receptor agonist: in vitro and in vivo pharmacological characterization and efficacy in animal models of Parkinson's disease.

期刊:The Journal of pharmacology and experimental therapeutics发表年份:2005作者:Robert B McCall; Keith J Lookingland; Paul J Bédard; Rita M Huff