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代谢疾病LLY-2707, a novel nonsteroidal glucocorticoid antagonist that reduces atypical antipsychotic-associated weight gain in rats.

期刊:The Journal of pharmacology and experimental therapeutics发表年份:2014作者:Dana K Sindelar; Mathew W Carson; Michelle Morin; Janice Shaw; Robert J Barr; Anne Need; Jesline Alexander-Chacko; Michael Coghlan; Donald R Gehlert

代谢疾病The GIP receptor displays higher basal activity than the GLP-1 receptor but does not recruit GRK2 or arrestin3 effectively.

期刊:PloS one发表年份:2014作者:Suleiman Al-Sabah; Munya Al-Fulaij; Ghina Shaaban; Hanadi A Ahmed; Rosalind J Mann; Dan Donnelly; Moritz Bünemann; Cornelius Krasel

代谢疾病Exposure to excess insulin (glargine) induces type 2 diabetes mellitus in mice fed on a chow diet.

期刊:The Journal of endocrinology发表年份:2014作者:Xuefeng Yang; Shuang Mei; Haihua Gu; Huailan Guo; Longying Zha; Junwei Cai; Xuefeng Li; Zhenqi Liu; Wenhong Cao

代谢疾病Characterization of [¹²⁵I]GLP-1(9-36), a novel radiolabeled analog of the major metabolite of glucagon-like peptide 1 to a receptor distinct from GLP1-R and function of the peptide in murine aorta.

期刊:Life sciences发表年份:2014作者:Rhoda E Kuc; Janet J Maguire; Keith Siew; Sheena Patel; David R Derksen; V Margaret Jackson; Kevin M O'Shaughnessey; Anthony P Davenport