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药效评价N-{4-Chloro-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}-2-hydroxybenzamide (CPPHA) acts through a novel site as a positive allosteric modulator of group 1 metabotropic glutamate receptors.

期刊：Molecular pharmacology发表年份：2008作者：Yelin Chen; Cyril Goudet; Jean-Philippe Pin; P Jeffrey Conn
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药效评价A structure-activity relationship study and combinatorial synthetic approach of C-terminal modified bifunctional peptides that are delta/mu opioid receptor agonists and neurokinin 1 receptor antagonists.

期刊：Journal of medicinal chemistry发表年份：2008作者：Takashi Yamamoto; Padma Nair; Josef Vagner; Tally Largent-Milnes; Peg Davis; Shou-Wu Ma; Edita Navratilova; Sharif Moye; Suneeta Tumati; Josephine Lai; Henry I Yamamura; Todd W Vanderah; Frank Porreca; Victor J Hruby
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药效评价A signaling-selective, nanomolar potent allosteric low molecular weight agonist for the human luteinizing hormone receptor.

期刊：Naunyn-Schmiedeberg's archives of pharmacology发表年份：2008作者：Chris J van Koppen; Guido J R Zaman; C Marco Timmers; Jan Kelder; Sietse Mosselman; Ruud van de Lagemaat; Martin J Smit; Rob G J M Hanssen
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药效评价Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4.

期刊：Molecular pharmacology发表年份：2008作者：Colleen M Niswender; Kari A Johnson; C David Weaver; Carrie K Jones; Zixiu Xiang; Qingwei Luo; Alice L Rodriguez; Joy E Marlo; Tomas de Paulis; Analisa D Thompson; Emily L Days; Tasha Nalywajko; Cheryl A Austin; Michael Baxter Williams; Jennifer E Ay
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