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药效评价The anxiolytic-like effects of the novel, orally active nociceptin opioid receptor agonist 8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol (SCH 221510).

期刊:The Journal of pharmacology and experimental therapeutics发表年份:2008作者:Geoffrey B Varty; Sherry X Lu; Cynthia A Morgan; Mary E Cohen-Williams; Robert A Hodgson; April Smith-Torhan; Hongtao Zhang; Ahmad B Fawzi; Michael P Graziano; Ginny D Ho; Julius Matasi; Deen Tulshian; Vicki L Coffin; Galen J Carey

药效评价7-Epiclusianone, a tetraprenylated benzophenone, relaxes airway smooth muscle through activation of the nitric oxide-cGMP pathway.

期刊:The Journal of pharmacology and experimental therapeutics发表年份:2008作者:Luciana Pontes Coelho; Magda Fráguas Serra; Ana Lúcia de Aguiar Pires; Renato Sérgio Balão Cordeiro; Patrícia Machado Rodrigues e Silva; Marcelo Henrique dos Santos; Marco Aurélio Martins

药效评价Characterization of a CNS penetrant, selective M1 muscarinic receptor agonist, 77-LH-28-1.

期刊:British journal of pharmacology发表年份:2008作者:C J Langmead; N E Austin; C L Branch; J T Brown; K A Buchanan; C H Davies; I T Forbes; V A H Fry; J J Hagan; H J Herdon; G A Jones; R Jeggo; J N C Kew; A Mazzali; R Melarange; N Patel; J Pardoe; A D Randall; C Roberts; A Roopun; K R Starr; A Teriakid

药效评价Inhibitors of GlyT1 affect glycine transport via discrete binding sites.

期刊:Molecular pharmacology发表年份:2008作者:Mario Mezler; Wilfried Hornberger; Reinhold Mueller; Martin Schmidt; Willi Amberg; Wilfried Braje; Michael Ochse; Hans Schoemaker; Berthold Behl