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药效评价Novel triazine JPC-2067-B inhibits Toxoplasma gondii in vitro and in vivo.

期刊:PLoS neglected tropical diseases发表年份:2008作者:Ernest J Mui; Guy A Schiehser; Wilbur K Milhous; Honghue Hsu; Craig W Roberts; Michael Kirisits; Stephen Muench; David Rice; J P Dubey; Joseph W Fowble; Pradipsinh K Rathod; Sherry F Queener; Susan R Liu; David P Jacobus; Rima McLeod

药效评价1-[1-Hexyl-6-(methyloxy)-1H-indazol-3-yl]-2-methyl-1-propanone, a potent and highly selective small molecule blocker of the large-conductance voltage-gated and calcium-dependent K+ channel.

期刊:The Journal of pharmacology and experimental therapeutics发表年份:2008作者:Haoyu Zeng; Earl Gordon; Zuojun Lin; Irina M Lozinskaya; Robert N Willette; Xiaoping Xu

药效评价Pharmacological evaluation of a novel cannabinoid 2 (CB2) ligand, PF-03550096, in vitro and in vivo by using a rat model of visceral hypersensitivity.

期刊:Journal of pharmacological sciences发表年份:2008作者:Akira Kikuchi; Katsuyo Ohashi; Yutaka Sugie; Hiromi Sugimoto; Hirofumi Omura

药效评价Substrate-targeting gamma-secretase modulators.

期刊:Nature发表年份:2008作者:Thomas L Kukar; Thomas B Ladd; Maralyssa A Bann; Patrick C Fraering; Rajeshwar Narlawar; Ghulam M Maharvi; Brent Healy; Robert Chapman; Alfred T Welzel; Robert W Price; Brenda Moore; Vijayaraghavan Rangachari; Bernadette Cusack; Jason Eriksen; Karen