其他Discovery of 7-tetrahydropyran-2-yl chromans: β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors that reduce amyloid β-protein (Aβ) in the central nervous system.
期刊：Journal of medicinal chemistry发表年份：2014作者：Allen A Thomas; Kevin W Hunt; Matthew Volgraf; Ryan J Watts; Xingrong Liu; Guy Vigers; Darin Smith; Douglas Sammond; Tony P Tang; Susan P Rhodes; Andrew T Metcalf; Karin D Brown; Jennifer N Otten; Michael Burkard; April A Cox; Mary K Geck Do; Darrin