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心血管疾病Identification and profiling of 3,5-dimethyl-isoxazole-4-carboxylic acid [2-methyl-4-((2S,3'S)-2-methyl-[1,3']bipyrrolidinyl-1'-yl)phenyl] amide as histamine H(3) receptor antagonist for the treatment of depression.

期刊:Bioorganic & medicinal chemistry letters发表年份:2013作者:Zhongli Gao; William J Hurst; Werngard Czechtizky; Daniel Hall; Nicolas Moindrot; Raisa Nagorny; Philippe Pichat; David Stefany; James A Hendrix; Pascal G George

心血管疾病Dynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels.

期刊:Proceedings of the National Academy of Sciences of the United States of America发表年份:2013作者:Haibo Yu; Zhihong Lin; Margrith E Mattmann; Beiyan Zou; Cecile Terrenoire; Hongkang Zhang; Meng Wu; Owen B McManus; Robert S Kass; Craig W Lindsley; Corey R Hopkins; Min Li

心血管疾病The inhibition of the potassium channel TASK-1 in rat cardiac muscle by endothelin-1 is mediated by phospholipase C.

期刊:Cardiovascular research发表年份:2013作者:Julia Schiekel; Moritz Lindner; Andrea Hetzel; Konstantin Wemhöner; Vijay Renigunta; Günter Schlichthörl; Niels Decher; Dominik Oliver; Jürgen Daut

心血管疾病HMG-CoA reductase inhibitors, simvastatin and atorvastatin, downregulate ABCG1-mediated cholesterol efflux in human macrophages.

期刊:Journal of cardiovascular pharmacology发表年份:2013作者:Wei Wang; Wei Song; Yu Wang; Lianfeng Chen; Xiaowei Yan