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药效评价Neurochemical, pharmacokinetic, and behavioral effects of the novel selective serotonin reuptake inhibitor BMS-505130.

期刊:Pharmacology, biochemistry, and behavior发表年份:2005作者:Matthew T Taber; Robert N Wright; Thaddeus F Molski; Wendy J Clarke; Patrick J Brassil; Derek J Denhart; Ronald J Mattson; Nicholas J Lodge

药效评价A role for the distal carboxyl tails in generating the novel pharmacology and G protein activation profile of mu and delta opioid receptor hetero-oligomers.

期刊:The Journal of biological chemistry发表年份:2005作者:Theresa Fan; George Varghese; Tuan Nguyen; Roderick Tse; Brian F O'Dowd; Susan R George

药效评价Effects of (2R)-(3-amino-2-fluoropropyl)sulphinic acid (AFPSiA) on transient lower oesophageal sphincter relaxation in dogs and mechanism of hypothermic effects in mice.

期刊:British journal of pharmacology发表年份:2005作者:Anders Lehmann; Ann Aurell Holmberg; Ulhas Bhatt; Marianne Bremner-Danielsen; Lena Brändén; Susanne Elg; Thomas Elebring; Kevin Fitzpatrick; William B Geiss; Peter Guzzo; Jorgen Jensen; Gunilla Jerndal; Jan P Mattsson; Karolina Nilsson; Britt-Marie O

药效评价Bioisosteric replacements of the pyrazole moiety of rimonabant: synthesis, biological properties, and molecular modeling investigations of thiazoles, triazoles, and imidazoles as potent and selective CB1 cannabinoid receptor antagonists.

期刊:Journal of medicinal chemistry发表年份:2005作者:Jos H M Lange; Herman H van Stuivenberg; Hein K A C Coolen; Tiny J P Adolfs; Andrew C McCreary; Hiskias G Keizer; Henri C Wals; Willem Veerman; Alice J M Borst; Wouter de Looff; Peter C Verveer; Chris G Kruse