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心血管疾病Voltage-gated Na+ channel β1B: a secreted cell adhesion molecule involved in human epilepsy.

期刊:The Journal of neuroscience : the official journal of the Society for Neuroscience发表年份:2011作者:Gustavo A Patino; William J Brackenbury; Yangyang Bao; Luis F Lopez-Santiago; Heather A O'Malley; Chunling Chen; Jeffrey D Calhoun; Ron G Lafrenière; Patrick Cossette; Guy A Rouleau; Lori L Isom

心血管疾病The bulky N6 substituent of cabergoline is responsible for agonism of this drug at 5-hydroxytryptamine 5-HT2A and 5-HT2B receptors and thus is a determinant of valvular heart disease.

期刊:The Journal of pharmacology and experimental therapeutics发表年份:2011作者:Alexandra Kekewska; Harald Hübner; Peter Gmeiner; Heinz H Pertz

心血管疾病Novel antiplatelet drug revacept (Dimeric Glycoprotein VI-Fc) specifically and efficiently inhibited collagen-induced platelet aggregation without affecting general hemostasis in humans.

期刊:Circulation发表年份:2011作者:Martin Ungerer; Kai Rosport; Andreas Bültmann; Richard Piechatzek; Kerstin Uhland; Peter Schlieper; Meinrad Gawaz; Götz Münch

心血管疾病Digoxin is not a substrate for organic anion-transporting polypeptide transporters OATP1A2, OATP1B1, OATP1B3, and OATP2B1 but is a substrate for a sodium-dependent transporter expressed in HEK293 cells.

期刊:Drug metabolism and disposition: the biological fate of chemicals发表年份:2011作者:Mitchell E Taub; Kirsten Mease; Rucha S Sane; Cory A Watson; Liangfu Chen; Harma Ellens; Brad Hirakawa; Eric L Reyner; Marton Jani; Caroline A Lee