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代谢疾病Discovery of novel and potent orally active calcium-sensing receptor antagonists that stimulate pulselike parathyroid hormone secretion: synthesis and structure-activity relationships of tetrahydropyrazolopyrimidine derivatives.

期刊：Journal of medicinal chemistry发表年份：2011作者：Masato Yoshida; Akira Mori; Etsuo Kotani; Masahiro Oka; Haruhiko Makino; Hisashi Fujita; Junko Ban; Yukihiro Ikeda; Tomohiro Kawamoto; Mika Goto; Hiroyuki Kimura; Atsuo Baba; Tsuneo Yasuma
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代谢疾病Discovery of novel N-β-D-xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes.

期刊：Journal of medicinal chemistry发表年份：2011作者：Chun-Hsu Yao; Jen-Shin Song; Chiung-Tong Chen; Teng-Kuang Yeh; Ming-Shiu Hung; Chih-Chun Chang; Yu-Wei Liu; Mao-Chia Yuan; Chieh-Jui Hsieh; Chung-Yu Huang; Min-Hsien Wang; Ching-Hui Chiu; Tsung-Chih Hsieh; Szu-Huei Wu; Wen-Chi Hsiao; Kuang-Feng Chu;
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代谢疾病Pharmacological inhibition of Kv1.3 fails to modulate insulin sensitivity in diabetic mice or human insulin-sensitive tissues.

期刊：American journal of physiology. Endocrinology and metabolism发表年份：2011作者：Stephen V Straub; Sylvie M Perez; Beijing Tan; Kimberly A Coughlan; Catherine E Trebino; Patricia Cosgrove; Joanne M Buxton; John M Kreeger; V Margaret Jackson
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代谢疾病N'-(arylsulfonyl)pyrazoline-1-carboxamidines as novel, neutral 5-hydroxytryptamine 6 receptor (5-HT₆R) antagonists with unique structural features.

期刊：Journal of medicinal chemistry发表年份：2011作者：Arnold van Loevezijn; Jennifer Venhorst; Wouter I Iwema Bakker; Cor G de Korte; Wouter de Looff; Stefan Verhoog; Jan-Willem van Wees; Martijn van Hoeve; Rob P van de Woestijne; Martina A W van der Neut; Alice J M Borst; Maria J P van Dongen; Natasja
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